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Symbol
Name
ID

Dnmt3b
DNA methyltransferase 3B
MGI:1261819

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Decreased circulating IgA level	Increased circulating IgM level	Abnormal bleeding	T lymphocytopenia	Reduced natural killer cell count	Acute myeloid leukemia	Thrombocytopenia	Elevated erythrocyte sedimentation rate
Disease(s) Associated with DNMT3B	Decreased circulating IgA level	Increased circulating IgM level	Abnormal bleeding	T lymphocytopenia	Reduced natural killer cell count	Acute myeloid leukemia	Thrombocytopenia	Elevated erythrocyte sedimentation rate
acute myeloid leukemia
autoimmune thrombocytopenic purpura
immunodeficiency-centromeric instability-facial anomalies syndrome 1
rheumatoid arthritis

Mouse Phenotypes		increased thymocyte apoptosis	small thymus	decreased thymocyte number	increased double-negative T cell number	decreased double-positive T cell number
Availability	Mouse Genotype	increased thymocyte apoptosis	small thymus	decreased thymocyte number	increased double-negative T cell number	decreased double-positive T cell number
	Dnmt3b^tm6Enl/Dnmt3b^tm6Enl
	Dnmt3b^tm7Enl/Dnmt3b^tm7Enl
	Dnmt3b^tm1Enl/Dnmt3b^tm6Enl
	Dnmt3b^tm1Enl/Dnmt3b^tm7Enl
	Dnmt3b^tm6Enl/Dnmt3b^tm7Enl

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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